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KMID : 0191120200350240231
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Journal of Korean Medical Science
2020 Volume.35 No. 24 p.231 ~ p.231
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A Case of Breakthrough COVID-19 during Hydroxychloroquine Maintenance
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Ahn Byeong-Yun
Kang Chang-Kyung
Seo Jong-Do
Choe Pyoeng-Gyun
Song Sang-Hoon
Park Wan-Beom
Park Sang-Won
Kim Nam-Joong
Oh Myoung-Don
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Abstract
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There have been controversies on the prophylactic effect of hydroxychloroquine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We describe a patient, 60-year old Korean woman, with coronavirus disease 2019 (COVID-19) who had been taking hydroxychloroquine for 6 months. Her serum and saliva concentrations of hydroxychloroquine were 280 μg/L and 4,890 μg/L, respectively. The present case raises concerns on hydroxychloroquine's role as a prophylactic agent for COVID-19.
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KEYWORD
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COVID-19, SARS-CoV-2, Hydroxychloroquine, Prophylaxis
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